Here's a clip of more from Misha's panel and he confirmed Robert Berens intentionally wrote that confession to mean romantic love not love in a "love ya bro" kind of way, confirmed Berens was going to leave the show for the final season but stayed so he could see that storyline through, confirmed that there were "stages" to how Destiel was treated in the show, it started out with fandom viewpoints, and then some winks and nods done by the show, and then eventually the writers were working in hints in that direction, he confirmed that yes he and Jensen discussed it, confirmed at a certain point they started playing into it more deliberately (seemingly in pace with the writers and the story hints) and reiterated he was really stunned that they were able to give Cas an open love declaration like that.
This is confirmation of writer intent. Confirmation the actors talked about it and knew about it and played into it, following the writers. Confirmation of creative deliberation. No this was not just some headcanon or fandom delusion.
People at the show, who make the show, were for it, and since the network was never going to let that be full-open mutually confirmed they did their best to convey it however they good. Snuck it in the back door. And we've already been told there was a lot of careful chess-playing to get the confession to air and they were all worried the network might cut it.
No amount of screaming and hate and denial from spnstanbunchanumbers on twitter is going to undo it or make Destiel shippers "delusional" for noticing, make it less canon.
The creatives at spn were on your side. This was not a queerbait. If you want to accuse anything of that, please aim it at the cw network and it's cap on representation and its queer erasure, because broadcast TV networks are like this. They are still like this, things do seem to be changing a little, as Misha said, things are becoming a bit more inclusive and open, but it's not like the whole system reforms all at once.
Cas being gay and canonically in love with Dean got erased in show-connected PR, and for a time, stifled on CE con stages. That doesn't make it not canonical.
FYI for historical context, the reason "canon Destiel" even became the major discourse that it did was because of how the show started handling it differently. That shift happened in Carver era. And Carver hired Berens.